초록 |
Tissue enigneered scaffold fabricated by 3D printing technology was widely used for the regeneration of injuries in tissue engineering field as their possibility to precisely design the optimized whole structure that could improve drawbacks in traditional therapy. Above all, 3D printing system as one of category in additive manufacturing has representatively attracted a lot of attention to the potential for using variety biomaterials regulating the mechanical and biological properties of the scaffold for tissue regeneration. For optimized fabrication of the scaffold to defected tissue, the various conditions of bioprinting could be controlled by bioink characteristics as well as specific parameter (i.e. strand width, distance between strands, the pattern of the strands, and degree of the interconnectivity) determining the properties of the scaffold. However, there were several problems such as restricting material choice as well as the design of the printing structure by using one kind of strand in the scaffold. To improve these functional limitations to fabricate the scaffold, we investigated the process that could provide the possibility for manufacturing the multifunctional scaffold. |