| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 가을 (10/09 ~ 10/10, 일산킨텍스) |
| 권호 |
33권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Development of microfluidics chip based biomimetic extracellular matrix systems and its application for monitoring cellular invasion and migration |
| 초록 |
Cell culture in microfluidics chip has large potential application in the tissue engineering. In this paper, we applied MMP sensitive-hyaluronic acid based hydrogel to integrated polymeric nanofiber membrane with the cell chip. Using flow diffusion in microfluidics chip generated nutrient gradient in hydrogel. Hydrogel in cell chip degrade by cell matrix metalloproteinase, it induce to cell migration and it is easy to cell invasion and cell alignment Key word : microfluidic chips, hydrogel, cell alignment. Acknowledgement: This study was supported by the Brain Korea 21 Project of the Ministry of Education and Human Resources Development, Republic of Korea. |
| 저자 |
이기화, 이광호, 신수정, 이상훈, 박용두, 선경
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| 소속 |
고려대 |
| 키워드 |
microfluidic chips; hydrogel; cell alignment
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| E-Mail |
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