학회 |
한국화학공학회 |
학술대회 |
2017년 가을 (10/25 ~ 10/27, 대전컨벤션센터) |
권호 |
23권 2호, p.2152 |
발표분야 |
재료 |
제목 |
Synthesis of Dual-Color-Emitting Carbon Nanodots via Surface Modification with 4-Octyloxyaniline for Multicolor Bioimaging and Optogenetic Control of Ion Channels |
초록 |
The electronic structure engineering of carbon nanodots (CNDs) has been one of the great issue for their various fields of applications. Here, we have developed intrinsically multicolor-emitting CNDs which emit two distinct colors via the surface electronic structure engineering with 4-octyloxyaniline. The so-called dual-color-emitting CNDs (DC-CNDs) could be stably encapsulated within water-soluble poly(styrene-co-maleic anhydride) (PSMA) enabling biomedical applications to in vitro and in vivo dual-color bioimaging and optogenetics. In vivo optical imaging could visualize the biodistribution of intravenously injected DC-CNDs@PSMA. Moreover, DC-CNDs could be successfully exploited for optogenetic applications via the wavelength-dependent activation of ion channels. As a new type of fluorophore, DC-CNDs offer a big insight into the design of multicolor-emitting materials for various optical and biomedical applications. |
저자 |
박윤상1, 김혜민1, 백송은1, 한슬기1, 정두엽1, 이시우2, 권우성2
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소속 |
1포항공과대, 2숙명여자대 |
키워드 |
화공소재 전반 |
E-Mail |
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원문파일 |
초록 보기 |