화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2010년 가을 (10/27 ~ 10/29, 대전컨벤션센터)
권호 14권 2호
발표분야 차세대 스텐트 소재
제목 Animal Restenosis Models and Drug-Eluting stent on Coronary Artery Disease
초록 A drug-eluting stent (DES) is a coronary stent (a scaffold) placed into narrowed, diseased coronary arteries that slowly releases a drug to block cell proliferation. This prevents fibrosis that, together with clots (thrombus), could otherwise block the stented artery, a process called restenosis The examination of neointimal hyperplasia in injured animal artery models has helped in our understanding of angioplasty and stenting mechanisms, and as DES technologies have arrived, they too have been advanced through the study of animal models. These models are useful for predicting adverse clinical outcomes in patients with DESs because suboptimal animal model studies typically lead to problematic human trials.
저자 배인호, 정명호, 박인규, 심두선, 김주한, 조은정
소속 전남대
키워드 Drug-Eluting Stent; Animal Model; Coronary Artery Disease
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