| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 봄 (04/10 ~ 04/11, 컨벤션 뷰로(대전)) |
| 권호 |
33권 1호 |
| 발표분야 |
의료용 고분자 |
| 제목 |
The characterization of PLGA/DBP hybrid scaffold for Tissue engineered biodisc |
| 초록 |
In this study, we developed the synthetic/natural hybrid scaffolds with poly (lactide-co-glycolide) (PLGA) and DBP for tissue engineered disc regeneration. Composite scaffolds of PLGA/DBP were manufactured by simple immersion method of PLGA scaffolds and DBP sponges were manufactured by solvent casting. We evaluated pore structure, porosity, water absorption ability and cell viability of two types of scaffolds. Through SEM and FTIR, it was confirmed that DBP solution was put into the pores of PLGA scaffold. Also, the effects of the impregnation of DBP solution on PLGA scaffolds were characterized through water absorption ability and cell viability. It seemed that DBP provided proper pore to PLGA scaffold and improved water absorption. A novel scaffold, which impregnated PLGA scaffold with DBP solution, was manufactured to ensure the possibility of application of degenerated IVD. Acknowledgement: This work was supported by SCRC (SC3100). |
| 저자 |
백미옥1, 김순희1, 소정원1, 임지예1, 홍현혜1, 정수현1, 최진희1, 이해방2, 강길선1
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| 소속 |
1전북대, 2한국화학(연) |
| 키워드 |
PLGA/DBP |
| E-Mail |
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