| 학회 |
한국화학공학회 |
| 학술대회 |
2010년 봄 (04/22 ~ 04/23, 대구 EXCO) |
| 권호 |
16권 1호, p.757 |
| 발표분야 |
재료 |
| 제목 |
Analysis of titanium disc surface modified by using L-DOPA after acid etching |
| 초록 |
A large number ofimplants have been studied by immobilizing of biomolecules on biomaterials. The L-DOPA was attached on surface-modified titanium as biomolecule to manufacture amine groups. The water contact angles of non-treated titanium disc (negative control), etched titanium disc (positive control) and titanium disc treated with a dopamine after etching process (experiment group) were 82.4±5.7°, 67.1±0.56° and 44.15±0.91° individually. We could finddopamine which had been adhered to titanium surface by AFM images. The quantifications of amine groups on positive control and experiment group were approximately 3g and 7.5g individually. The number of human bone marrow mesenchymal stem cells (BM-MSCs) on the experiment group was much higher than that of cells on any other groups. According to the data, our report proposed that there may be a causal link between increased dopamine content and cell proliferation in BM-MSCs. In addition, the dopamine can make the titanium surface more hydrophilic and enhance the adhesion of BM-MSCs cells. |
| 저자 |
김성현1, 박정극1, 정현석2, 홍국선3, 이종호3, 서영권1
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| 소속 |
1동국대, 2국민대, 3서울대 |
| 키워드 |
Dental implant; Titanium; Biomaterial; Dopamine; Biocompatibility
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| E-Mail |
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| 원문파일 |
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