| 학회 |
한국고분자학회 |
| 학술대회 |
2014년 봄 (04/10 ~ 04/11, 대전 컨벤션센터) |
| 권호 |
39권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Preparation of Quantum Dot-embedded Polystyrene Nanobeads for Bioimaging |
| 초록 |
We demonstrate the development of heavy metal-free quantum dot (QD)-embedded polystyrene (PS) nanobeads for the purpose of introducing stable and bright fluorescence imaging probes. The design compromises encapsulating biocompatible poloxamers and cross-linked PS nanomatrices in which QDs are incorporated. PS nanobeads of sub-10 nm with a narrow size distribution were synthesized by emulsion polymerization with a nonionic surfactant. For a postsynthetic process, CuInS2/ZnS QDs were loaded into the nanobeads which were swollen in a co-solvent system. As-prepared nanoprobes exhibit high colloidal stability and corresponding fluorescence maintenance as well. Efficient in vivo tumor-targeted imaging was achieved by using the newly developed nanocomposites, being consequently presented as potential candidates toward in vivo tumor diagnosis. |
| 저자 |
김영선, 서영훈, 김세훈
|
| 소속 |
한국과학기술(연) |
| 키워드 |
quantum dot; polystyrene bead; poloxamer; fluorescence imaging
|
| E-Mail |
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