초록 |
In this study, we introduce a temperature-responsive novel nanoemulsion film (NEF) system. The NEFs were fabricated by alternative layering of nanoemulsion with bacterial cellulose nanofibirils (BCNFs) through the layer-by-layer deposition. Basically, the NEFs reinforced with BCNFs showed more increased moduli than those with polyelectrolytes only, which stems from the mechanical properties of BCNFs. The NEFs fabricated in this study exhibited a typical Spinodal decomposition behavior. We could observe that when heat is applied to the NEF, the nanoemulsion drops uniformly diapered in the 3D network structure of BCNF readily interdiffused to form the oil domains. Thus, this behavior of BCNFs resulted in the drastic decrease in the phase separation rate and formation of smaller oil domains. Finally, we demonstrated that the NEFs could be used not only for development of a patch-type drug delivery system, but also for the development of a temperature-responsive novel adhesive film. |