| 학회 |
한국고분자학회 |
| 학술대회 |
2019년 가을 (10/09 ~ 10/11, 제주컨벤션센터) |
| 권호 |
44권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Functionalized PLCL-Laminin nanofiber for the benefit in neuritogenesis enhancement |
| 초록 |
In the past decade, electrospun nanofiber composed of various biomaterials has attracted widespread interest as promising scaffolds for cell and tissue engineering since electrospun nanofiber sheets have a very large surface area as well as similar structure with the natural extracellular matrix. In this study, poly(lactide-co-ɛ-caprolactone, PLCL) nanofiber sheets with laminin were fabricated by electrospinning. The physicochemical properties of PLCL-Lam nanofiber sheets were analyzed, and the cellular behaviors of HT22 hippocampal cells on the nanofiber sheets were investigated. Our results showed that HT22 hippocampal cell behaviors were remarkably promoted on the nanosheets. In conclusion, it is suggested that PLCL-Laminin nanofiber sheets can be promising candidates as neural tissue engineering scaffolds. |
| 저자 |
송수진1, 이유빈1, 강문성1, 서희정1, 현승휴2, 한동욱1
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| 소속 |
1부산대, 2가고시마대 |
| 키워드 |
PLCL; Laminin; nanofiber; neuronal cell; neuritogenesis
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| E-Mail |
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