학회 | 한국화학공학회 |
학술대회 | 2012년 가을 (10/24 ~ 10/26, 부산 BEXCO) |
권호 | 18권 2호, p.2306 |
발표분야 | 재료 |
제목 | Graphene Oxide Cell Culture Substratum for Human Adipose-Derived Stem Cells |
초록 | Nanoscale topography of artificial substrates can greatly influence the fate of stem cells including adhesion, proliferation, and differentiation. Thus the design and manipulation of nanoscale stem cell culture platforms or scaffolds are of great importance as a strategy in stem cell and tissue engineering applications. In this poster, we propose that a graphene oxide (GO) film is an efficient platform for modulating structure and function of human adipose-derived stem cells (hASCs). The hASCs grown on the GO films showed increased adhesion, indicated by a large number of focal adhesion, and higher correlation between the orientations of actin filaments and vinculin bands compared to hASCs grown on the glass (uncoated GO substrate). [Acknowledgement] This research was supported in part by the Basic Science Research Program and (2011-0008994) and Mid-career Research Program (2011-0028752) through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology, and in part by the Center for Green Airport Pavement Technology (CGAPT) of Chung-Ang University. |
저자 | 최경순1, 김장호2, 김연주3, 임기택2, 선우훈2, 박연실1, 김덕호4, 정필훈2, 조정수2, 정연훈3, 정종훈2, 김수영1 |
소속 | 1중앙대, 2서울대, 3아주대, 4워싱턴대 |
키워드 | cell culture; graphene oxide; human stem cells |
원문파일 | 초록 보기 |