화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2021년 봄 (05/12 ~ 05/14, 부산 벡스코(BEXCO))
권호 25권 1호
발표분야 포스터-정밀화학
제목 Multi-Functional Nanoparticles with Fluorescent Silica Shell for Tri-functional Bio-applications
초록 We have developed the magnetic-SERS-fluorescence (MF-SERS) nanoparticles with fluorescent silica nanospheres. It contains multi-layer that superparamagnetic Fe3O4 NPs, Ag NPs and fluorescent shell on the silica NPs. The MF-SERS NPs revealed strong fluorescence from RICR as well as SERS signals from the silver NPs and superparamagnetism from Fe3O4. The MF-SERS NPs were absorbed by cells and external magnetic field was successfully appealed and separated the NPs. Here, we could detect these signals that SERS and fluorescence from NPs with cells and CD44 antibody-conjugated MF-SERS NPs that selectively targeted MDA-MB-231 cells. Based on these properties the MF-SERS NPs were confirmed that multi-functional NPs for detection and analysis of cancer cells.
저자 김우연, 성보미, 김윤희, 복성재, 함경민, 임다경, 전봉현
소속 건국대
키워드 tri-functional; nanoparticle; magnetic; fluorescence
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