| 초록 |
Silver nanoparticles (AgNPs) are extensively used for various biological activities. However, the use of toxic chemicals for AgNPs synthesis limits their biological applications. Thus, novel biopolymers are explored for a reliable, efficient and rapid synthesis process for AgNPs. Here, we synthesized dialdehyde-modified laminarin (DLAM) for in situ, simple, and rapid synthesis of ultrasmall-sized AgNPs with high silver percentage using DLAM as a reducing and stabilizing agent. The FT-IR peaks confirmed the presence of dialdehyde groups on the modified laminarin. The UV-vis spectroscopy showed surface plasmon resonance peak at around 409 nm and the XRD data showed 2θ peaks of (111), (200), (220) and (311) face centered cubic planes of Ag in AgNPs-DLAM. The HR-TEM and AFM images of AgNPs-DLAM showed spherical AgNPs of <10 nm size. The AgNPs-DLAM showed high antibacterial activities against Escherichia coli and Staphylococcus aureus via causing structural changes in bacterial cells as shown by SEM images. The AgNPs-DLAM also inhibited biofilm formation and enhanced the migration of human keratinocytes HaCaT cells, indication efficient wound healing property. |
