| 학회 |
한국고분자학회 |
| 학술대회 |
2012년 가을 (10/11 ~ 10/12, 창원컨벤션센터) |
| 권호 |
37권 2호 |
| 발표분야 |
고분자합성 |
| 제목 |
Hyperbranched Polyglycidol/Lecithin Hybrid Liposomes for Controlled Drug Delivery |
| 초록 |
Liposome is a spherical vesicle composed of a bilayer membrane and commercially important drug delivery system because of their biocompatiability. Lecithin liposome was fabricated by self assembly method. Liposomes are capable of encapsulating hydrophilic drugs in their inner aqueous compartment in their lipid bilayer. To increase stability of drug loaded liposome, we incorporated hyperbranched polyglycidol (HBP) with lecithin. The average diameter, polydispersity index and zeta potential of liposome was determined using dynamic light scattering analyzer. The morphologies of liposomes were observed by scanning electron microscope and transmission electron microscope. |
| 저자 |
송송이1, 김일2
|
| 소속 |
1부산대, 2합성고분자 생물접합 하이브리드 재료사업단 |
| 키워드 |
Lecithin; Hyperbranched Polyglycidol (HBP); Liposome; Self assembly; Drug delivery
|
| E-Mail |
|
