| 초록 |
Hypoxia, oxygen insufficient condition, is important indicator of diseases. In case of tumor tissue, rapid growing of tissue leads to lack of oxygen supply and that induces hypoxia condition. Therefore, design of molecular indicator of hypoxia will be useful for tumor study. Because fluorescent bioprobes have attractive features, such as high sensitivity, non-invasive imaging in live cell condition, high selectivity, we decided to develop fluorescent bioprobes for monitoring hypoxic condition. In particularly, Seoul-Fluor system was chosen for platform to develop the bio-probe. |
