초록 |
There are serious problems in the industrial fermentation of filamentous microorganism such as antibiotics, enzymes and food additives.Today, one of the most challenging tasks is to solve problem for highly viscous fermentation broths. This problem may lead to oxygen limitationand heterogeneity within the fermentor before the carbon source being exhausted. Therefore, to maintain well-mixing condition and prevent oxygenlimitation inside the fermentor, dilution with water or increasing agitation speed or high aeration can be needed. Also, control of growth ratecan prevent the highly viscous fermentation broths. Temperature is one of the important environmental factors affecting growth in the microorganism.In the study, we investigated the effect of temperature on the growth and the production of Monascus sp. J101 in a stirred vessel. Also, we performedrheological analysis and investigated morphological characterization of fermentation broths cultivated at different temperatures.
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