화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2019년 봄 (04/24 ~ 04/26, 제주국제컨벤션센터)
권호 25권 1호, p.704
발표분야 재료(Materials)
제목 Fabrication of Fluorescent Labeled Bi-compartmental Particles via the Micromolding Method
초록 Fluorescent labeled particles are materials widely used in the drug delivery system, self-assembly of particles, biosensors, and bioimaging. However, it is difficult to use it to study more complex particle systems using only single fluorescent labeled particles. Thus, there is an increasing demand for multi-fluorescent labeled multi-compartmental particles.  
Herein, this study presents fabrication of bi-compartmental particles labeled by two kinds of fluorescence using the micromolding method. Compartmentalization of the fluorescence in bi-compartmental particles is verified by qualitative and quantitative analysis. Finally, by analyzing fluorescence intensity, we can confirm that fluorescence is stably expressed even after 4 weeks.
In conclusion, we fabricate bi-compartmental particles in which two kinds of fluorescence is completely compartmentalized and verify the fluorescence stability of these particles. We anticipate that these particle can be widely utilized in multi-step drug delivery system, analysis for 3 dimensional Brownian motion of particles, identification of complex self-assembled structures.
저자 심규락, 정성근, 홍우경, 강경구, 이창수
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