| 학회 |
한국화학공학회 |
| 학술대회 |
2010년 가을 (10/21 ~ 10/22, 대전컨벤션센터) |
| 권호 |
16권 2호, p.2344 |
| 발표분야 |
환경 |
| 제목 |
A Novel Strategy to Realize Ratiometric Detection Using Metallic Nanoparticles |
| 초록 |
Ratiometric detection that typically measures emission intensities of fluorescent probe at two different wavelengths can provide built-in correction for environmental variations of a sample and probe intrinsic to detection systems, permitting quantitative measurements. Although localized surface plasmon resonance (LSPR) detection using metallic nanoparticles has proven more sensitive than fluorescence, most of LSPR-based detection mechanisms rely on random aggregation of many particles, which has been problematic for quantitative measurements. Here we demonstrate an innovative strategy to design ratiometric detection system using dimeric nanoprobes that gold and polystyrene nanoparticles are attached together. Upon exposure to an analyte, pairs of the nanoprobes can be assembled, resulting in new absorbance peak at longer wavelength. By measuring intensities of two absorbance peaks, ratiometric detection can be accomplished.
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| 저자 |
김기훈1, 이수승2, 양영인2, 정은혜1, 이종협2, 최연호3, 강태욱1
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| 소속 |
1서강대, 2서울대, 3고려대 |
| 키워드 |
Ratiometry sensor; metal/non metal hybrid particle
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| E-Mail |
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| 원문파일 |
초록 보기 |
