| 초록 |
Considerable efforts have been made in developing mechanical and biological properties of acrylic-based bone cement. Novel inclusion complex based on triethylene glycol dimethacrylate (TEGDMA) and α- or β-cyclodextrin was synthesized characterized and used to formulate resin composites with amino acid based monomer, acryloyl beta-alanine (ABA), and inorganic filler, such as hydroxyapatite (HA) which was proven to be a biocompatible and osteoconductive material. The optimal formulation was determined based on monomer/diluent ratio, initiator concentration, and filler level using compressive strength (CS) and curing time (CT) as screening tools. Shrinkage, exotherm, diametral tensile strength (DTS) and aging of the formed composite cements were also evaluated. This novel cement may be a potential candidate for orthopedic restoration if its biological performance is good and the formulation is optimized. |
