| 학회 |
한국고분자학회 |
| 학술대회 |
2018년 가을 (10/10 ~ 10/12, 경주컨벤션센터) |
| 권호 |
43권 2호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Study on Interactions between cell and Polymer-coated Atomic Force Microscopy Probe |
| 초록 |
A study on cellular interactions (such as quantified cell adhesion, cell aggregation or direct drug injection theory) is important in microbiology, medicine and biotechnology. Atomic Force Microscopy (AFM) is a powerful tool for measuring the cellular interaction force between a single cell and AFM probe. Using this system, researchers have studied the interaction forces between cell membrane and biomaterial coated AFM tip on a single cell. Herein, we present a new and simple method that uses E-beam irradiation to fabricate the polymer-coated Dip-Pen Nanolithography (DPN) probe. Using polymer-coated DPN probe, we have generated patterns of fluorescent materials. We also show how to capture a single cell and directly inject a target material into the cell by polymer-coated AFM tip. All analyses were performed using atomic force microscopy, confocal microscopy and scanning electron microscope (SEM). This was supported by Korea National University of Transportation in 2018. |
| 저자 |
곽효빈, 강필선, 오신석, 김소연, 김경민, 임정혁
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| 소속 |
한국교통대 |
| 키워드 |
Cell interactions; AFM; E-beam irradiation
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| E-Mail |
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