| 학회 |
한국고분자학회 |
| 학술대회 |
2012년 봄 (04/12 ~ 04/13, 대전컨벤션센터) |
| 권호 |
37권 1호 |
| 발표분야 |
의료용고분자 부문위원회 |
| 제목 |
Development of Injectable Cell/Microsphere Aggregates for Tissue Engineering |
| 초록 |
Injectable delivery systems have been widely exploited in tissue engineering, as cells can be delivered into the body in a minimally invasive manner. In this research, we propose to use RGD-alginate microspheres to form cell aggregates as an injectable. Alginate is a natural polymer that has been extensively used in many biomedical applications. Alginate microspheres were fabricated using the water-in-oil emulsion method and modified with RGD peptides. The aggregation behavior of RGD-alginate microspheres/chondrocytes mixtures was measured by a rotational rheometer and the efficacy of the mixtures in cartilage regeneration in mice was tested. |
| 저자 |
우은경, 박홍현, 이근용
|
| 소속 |
한양대 |
| 키워드 |
alginate; microsphere; RGD; tissue engineering
|
| E-Mail |
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