| 학회 | 한국화학공학회 |
| 학술대회 | 2007년 봄 (04/19 ~ 04/20, 울산 롯데호텔) |
| 권호 | 13권 1호, p.315 |
| 발표분야 | 분리기술 |
| 제목 | Removal of BSA using solid-phase extraction in microfluidic device |
| 초록 | Serum albumin is one of the most abundant serum proteins which block the expression other important biomarkers. The objective of this study is to remove serum albumin effectively by using solid phase extraction in microfluidic devices. In-situ photo-polymerized adsorbent was used to remove BSA. The adsorption capacity of the photo-polymerized adsorbent was examined with the effect of pH and concentration in BSA solution, and adjusting the concentration of monomer such as hydrophilic AMPS and AAm in adsorbent. Optimal conditions were applied to solid phase extraction in microchannel. Selective removal in bicomponent with bovine serum albumin and bovine γ-globulin was performed with adjusting pH. |
| 저자 | 이은주1, 허윤석1, 전영시1, 원효진1, 홍연기2, 홍원희1, 김도현1 |
| 소속 | 1한국과학기술원, 2충주대 |
| 키워드 | BSA; solid-phase extraction; microfluidic device |
| 원문파일 | 초록 보기 |
