| 학회 | 한국화학공학회 |
| 학술대회 | 2017년 봄 (04/26 ~ 04/28, ICC 제주) |
| 권호 | 23권 1호, p.442 |
| 발표분야 | 생물화공 |
| 제목 | Kinetics and Thermodynamics of Ultrasound-Assisted Paclitaxel Extraction from Taxus chinensis |
| 초록 | Ultrasound-assisted extraction (UAE) of paclitaxel from Taxus chinensis has been investigated to understand the effect of ultrasound power and temperature on kinetics and thermodynamics of extraction. The paclitaxel concentration-time data were analyzed using a second order kinetic model to determine extraction constant. A diffusion model was utilized to determine diffusion coefficient taking into account of both washing and diffusion phases together. The thermodynamic analysis showed that the enthalpy change (ΔH^0) and entropy change (ΔS^0) were both positive, while the Gibbs free energy change (∆G^0) was negative and decreased when increasing the temperature and ultrasound power. The results indicated that the UAE process for recovering paclitaxel from biomass was endothermic, irreversible, and spontaneous. Acknowledgment This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (Grant Number: 2015016271). |
| 저자 | 유경완, 김진현 |
| 소속 | 공주대 |
| 키워드 | 생물화공 |
| 원문파일 | 초록 보기 |
