| 학회 |
한국공업화학회 |
| 학술대회 |
2017년 가을 (11/08 ~ 11/10, 부산 벡스코(BEXCO)) |
| 권호 |
21권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Fibroblast-derived Extracellular Matrix Grafting on PLGA Scaffolds for Renal Tissue Regeneration |
| 초록 |
Renal diseases have been recognized as major health issues. In this study, three-dimensional porous poly(lactide-co-glycolide) (PLGA) scaffold incorporated with magnesium hydroxide were developed and then grafted with fibroblast-derived extracellular matrix (FDM) for further improved biocompatibility. PLGA scaffold with FDM layer demonstrated significantly increased adhesion and viability of urine derived nephron progenitor cells. These results suggest that introduction of FDM layer would be effective for renal tissue regeneration. |
| 저자 |
김윤아1, 한철민1, 고원건2, 유승권3, 한동근4, 정윤기1
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| 소속 |
1한국과학기술(연), 2연세대, 3고려대, 4차의과학대 |
| 키워드 |
renal tissue regeneration; porous scaffold; fibroblast extracellular matrix; nephron progenitor cells
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| E-Mail |
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