화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2017년 가을 (11/08 ~ 11/10, 부산 벡스코(BEXCO))
권호 21권 2호
발표분야 생체재료_포스터
제목 Improvement of biofunctionality of chitosan-incorporated collagen matrix.
초록 Natural polymers are highly biocompatible and can be used as biomaterials for the regeneration of soft and hard tissues. Collagen is one of the most widely used naturally derived polymers since it has cell adhesion moiety and can promote cellular activity. In this study, we incorporated chitosan into collagen matrix at different ratios of collagen to chitosan in order to improve cell proliferation. The matrix was physically stabilized via chemical cross-linking. The effects of chitosan incorporation on the physicochemical properties of the matrix, including the water uptake, degradation rate, and geometrical appearance, were evaluated. In vitro assessments on fibroblast adhesion and proliferation were performed.
저자 성정희, 공영진, 김수정, 배승훈, 유혜진, 함정선, 이우걸
소속 단국대
키워드 collagen; chitosan; hydrogel; fibroblast
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