화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2008년 봄 (04/23 ~ 04/25, 제주ICC)
권호 14권 1호, p.45
발표분야 고분자
제목 Synthesis of water soluble PEGylated magnetic complexes using mPEG-fatty acid for biomedical applications
초록 We report the successful fabrication of the various types of water-soluble PEGylated magnetic complexes (PMCs) for magnetism related biomedical applications. Various types of PMCs were synthesized and teated to accomplish phase transfer from organic to aqueous phase using monomethoxy polyethylene glycol (mPEG)-fatty acid amphiphilic block copolymers (PFs) through conjugation of the hydroxyl group of mPEG with the carboxyl group of fatty acids. Fatty acids are known as low toxic and essential components in human body systems, including the immune system and in blood pressure regulation. As fatty acids, moreover we used hexanoic acid, lauric acid, stearic acid and oleic acid which were widely employed for hydrophobic ligands.
저자 임은경, 양재문, 박미예, 박요셉, 서진석, 윤호근, 허용민, 함승주
소속 연세대
키워드 Fatty acid; Magnetic resonance image; Magnetic nanocrystal; monomethoxy polyethylene glycol (mPEG); Magnetic complex
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