화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2010년 봄 (04/08 ~ 04/09, 대전컨벤션센터)
권호 35권 1호
발표분야 의료용 고분자 부문위원회
제목 In vitro assessment of antibacterial PHBV/rutin nanofibrous scaffolds for tissue engineering
초록 Rutin (R) exhibits a wide range of biological activities including anticarcinogenic, anti-inflammatory and antiviral actions. The purpose of this study is to investigate the effect of rutin concentrations (1 wt%, 3 wt%) on the antibacterial activity of poly(3-hydroxybutyrate-co-hydroxyvalerate) (PHBV) scaffolds. Antibacterial activity was evaluated by using Staphylococcus aureus and Klebsiella pneumoniae. Furthermore, the qualitative ongrowth of human KB epithelial cells was done to study in vitro cytotoxicity of the scaffolds. As the results, PHBV/R scaffolds completely inhibited the proliferation of Staphylococcus aureus and Klebsiella pneumoniae. In addition the PHBV/R scaffolds used in this study did not show any cytotoxicity
저자 채원표, 백진영, 싱즐챠이, 강인규
소속 경북대
키워드 cytotoxicity; PHBV; Antibacterial
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