| 학회 |
한국고분자학회 |
| 학술대회 |
2009년 봄 (04/09 ~ 04/10, 대전컨벤션센터) |
| 권호 |
34권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Porous Poly (lactic-co-glycolic acid) Microsphere loaded Demineralized Bone Matrix Particles for Bone Tissue Engineering |
| 초록 |
Porous, poly(lactic-co-glycolic acid)(PLGA)/demineralized bone matrix particle(DBMp) composite microspheres(DBMp/PLGA MS) are useful for directly filling tissues as well as for delivering cells and bioactive moleculates in tissue engineering. DBM is widely used as a bone graft substitute in orthopaedics and dentistry. One of the limitations to the tissue regeneration using DBMp is the maintenance within the defect site. Any migration of particles from the area could compromise the graft success because of inadequate regeneration of the defect and potential ectopic bone formation. To address this problem, DBMp materials have been developed that use a carrier to keep the particles together at the graft site. The goal of this study is to fabricate porous DBMp/PLGA MS for bone regeneration. |
| 저자 |
정홍희1, 이근수2, 김일환2, 최연락2, 심영복2, 장주웅2, 이광일2
|
| 소속 |
1네온메디칼, 2코리아본뱅크 |
| 키워드 |
Microsphere; Demineralized bone matrix; bone regeneration
|
| E-Mail |
|
