초록 |
With the development of three-dimensional printing (3d printing) technology, the combination of this technique and biomedical approaches, such as biomaterial, tissue engineering. The most important part of 3d bioprinting is the bioink, the main material for printing. To allowing contain living cells or cultivates cells directly on bioink, it requires biocompatibility and cytotoxicity. In this study, we present a bioink, which has good processability. This bioink can transform into hydrogel spontaneously in physiological aqueous condition without any additional gelation process. Moreover, it is able to keep the printed shapes stably after direct writing in normal cell culture media. Proposing bioink is based on a chitosan, a natural polymer. The chitosan was mainly used as scaffold for tissue engineering and wound healing in biomaterial field. |