| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 가을 (10/06 ~ 10/08, 대구컨벤션센터(EXCO)) |
| 권호 |
40권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Application of Biodegradable Polymeric Microsphere as Embolic Material |
| 초록 |
Chemoembolization is one of promising therapeutic methods for hepatocellular carcinoma, which occludes the artery suppling nutrition to tumor tissue with micro-beads or viscous oils. This method has some advantages that it does not demand any surgical operations or radiations. Since embolization is usually treated several times during a predetermined period of time, the blocking materials should be cleared after a few weeks so that it does not makes any disturbance to the secondary injection. In this research, we used FDA-approved biodegradable polymer and formulated micro-sized beads. In addition, the radiopacity was given to microsphere during the particle formation for convenience and safety of treatment. The size of beads was around several hundred micrometers, and the beads contained enough x-ray visible substances to be visualized by a C-arm x-ray device. In conclusion, we confirmed the potential of this biodegradable polymeric bead for more effective cancer therapy. |
| 저자 |
안철희1, 제환준2, 김영일2, 이명수2, 전성익1
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| 소속 |
1서울대, 2서울대병원 |
| 키워드 |
Chemoembolization; CT contrast agent; Polymeric bead
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| E-Mail |
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