| 학회 |
한국공업화학회 |
| 학술대회 |
2015년 가을 (11/04 ~ 11/06, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 |
19권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
One-Pot Modification of Activation-Free Biofunctionalizable, Nonbiofouing Copolymeric Films via Surface-initiated ARGET ATRP on Gold and Selective Bioconjugation on their Films |
| 초록 |
We prepared activation-free copolymeric films with high selectivity to biomolecules by surface-initiated Activators ReGenerated by Electron Transfer Atom Transfer Radical Polymerization (SI-ARGET ATRP) by monomers such as N-acryloxysuccinimide (NAS) and oligo(ethylene glycol) methyl ether methacrylate (OEGMEMA). Subsequently the coupling of a biotin ligand was directly performed on poly(NAS-co-OEGMEMA) films without an activation step, resulting in biotinylated, poly(NAS-co-OEGMEMA) films. Micro-contact printing (µCP) of the biotin ligand on the poly(NAS-co-OEGMEMA) films and subsequent immersion the biotin-patterned films in rhodamine-conjugated streptavidin solution was performed for evaluating feasibility of selective bioconjugation, resulting in microarray of protein. |
| 저자 |
최인성, 이봉수
|
| 소속 |
KAIST |
| 키워드 |
: Activation-Free; ARGET ATRP; Selective Bioconjugation
|
| E-Mail |
|
