| 초록 |
A new polythiophene with pendant N-hydroxysuccinimide ester groups was synthesized by polymerization of its monomer with FeCl3 in chloroform. The resulting polymer was soluble in common organic solvents (DMSO, DMF, chloroform, etc.) and characterized by NMR, FT-IR and GPC. This polymer is able to react with amine-bearing molecules to yield new polythiophene derivatives. The reaction of the polythiophene with various amines was confirmed by UV-visible spectrophotometer. After the polythiophene thin film was treated with various amine solutions, their surface properties were investigated by contact angle measurement. A thin film of the polythiophene was prepared on a gold-coated quartz cell for immobilization of anti-CRP (C-reactive protein) and the binding behavior of CRP on the surface was monitored by use of SPR (surface plasmon resonance) sensor system. |
