| 학회 |
한국공업화학회 |
| 학술대회 |
2016년 가을 (10/26 ~ 10/28, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 |
20권 2호 |
| 발표분야 |
(생체재료) 다기능성 생체재료 |
| 제목 |
Appropriately Released Bioactive Molecules for Tissue Regeneration and Pain Control |
| 초록 |
In recent years, sustained release of bioactive molecules is very common concept in tissue engineering and pharmaceutical fields. However, little is known regarding the appropriate release profiles for optimized effect of the purposes, because of the rapid activity change of bioactive molecules; the lack of well-defined delivery system that can preserve their bioactivity for sufficient period, as well as precisely regulate the release behavior of the molecules. In this presentation, our current studies to determine the optimum release profile for each purpose will be discussed as follows: i) Controlling oxygen release from hollow microparticles for prolonged cell survival in tissue engineering 3D matrix; ii) Development of porous beads to provide regulated BMP-2 stimulation for varying durations: In vitro and in vivo studies for new bone formation; iii) Lidocaine/multivalent ion complex as a potential strategy for prolonged local anesthesia. |
| 저자 |
이혜영1, 장유진1, 김호용1, 이진호2, 변준호3, 오세행1
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| 소속 |
1단국대, 2한남대, 3경상대 |
| 키워드 |
Tissue engineering; oxygen releasing; porous bead; BMP-2; Lidocaine
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| E-Mail |
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