| 학회 |
한국화학공학회 |
| 학술대회 |
2005년 가을 (10/21 ~ 10/22, 인하대학교) |
| 권호 |
11권 2호, p.2063 |
| 발표분야 |
생물화공 |
| 제목 |
Stabilization of Vitamin-C by inclusion complex formation using supercritical CO2 |
| 초록 |
Supercritical fluid process is multipurpose technology which can be used in cosmetic and pharmaceutical industry. This process as eco-friendly and non-toxic technique is remarkably suitable to the field of this kind of industries where bio-compatibility is important. The bio-availability of Vitamin-C is decreasing with the lapse of time because it is spontaneously oxidized in the presence of oxygen. Therefore, it is very important to prevent Vitamin-C from being oxidized. In this study, supercritical fluid process was employed as the main technology, and the hydroxyprophyl-β-cyclodextrin was employed as a protector for stabilization of Vitamin-C and formed inclusion complex with Vitamin-C. Because supercritical fluid process is free from oxygen and moisture, it is able to prevent Vitamin-C from being degraded in the process of preparation. As a necessary consequence, this is a more effective stabilizing process than existing ones such as a solvent evaporation process, and a spontaneous solvent diffusion process, etc. We carried out the experiment by both a solvent evaporation process and a supercritical fluid process and compareded the results. To evaluate the stability of prepared samples, we looked at the degradation of Vitamin-C. |
| 저자 |
양준모, 김석윤, 김은미, 변지현, 이상윤, 유종훈, 임교빈
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| 소속 |
수원대 |
| 키워드 |
Vitamin-C; Supercritical; Inclusion complex; cyclodextrin
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| E-Mail |
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| 원문파일 |
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