화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2015년 가을 (10/06 ~ 10/08, 대구컨벤션센터(EXCO))
권호 40권 2호
발표분야 의료용 고분자 부문위원회 I (영어발표)
제목 Enhanced Cellular Affinity for Ferroelectric Poly(vinylidene fluoride)/Multi-walled Carbon Nanotube Composite Scaffolds
초록 Polar poly(vinylidene fluoride) (PVDF)/multiwalled carbon nanotube (MWCNT) composites were prepared for the cell growth scaffolds. By controlling the processing conditions and the amount of MWCNT, total contents of polar beta-phase showing the ferroelectric properties was varied. All nanocomposite scaffolds induced vigorous cell metabolic activities in 7 days culture compared to a nonpolar scaffold (alpha-phase PVDF). Image saliency analysis revealed that fibroblasts on the PVDF/MWCNT nanocomposite films were more actively occurred with high beta-phase composites. Cell adhesion and proliferation measurement with MTT (Methylthiazolyldiphenyl-tetrazolium bromide) assay coincidentally responded to the amount of beta-phase in the polarized PVDF composite films. Strong correlation between the ferroelectric properties (hence the amount of beta-phase) and the cell activities (fibronectin adsorption towards the cell-nanocomposites interface) was observed.
저자 임준영, 서용석
소속 서울대
키워드 Ferroelectricity; Cell growth; Scaffold; Stiness
E-Mail