| 초록 |
Yarrowia lipolytica which has been extensively used as the model oleaginous yeast for producing heterologous proteins has the capability to accumulate lipids (lipidbody, peroxisome etc) up to 50% of the DCW (dry cell weight). In addition, Y. lipolytica can be easily manipulated in gene deletion and insertion because it possesses a haploid genome and its genome sequence was completed and it is also known as GRAS (generally recognized as safe). Therefore, Y. lipolytica can be a high potential host strain in producing oleaginous (hydrophobic) and high value-added compounds used in cosmetic and nutraceutical materials which are hydrophobic and produced from plants by conventional extraction processes. Recently, these compounds were produced in microorganism and it is well known that DuPont produced omega-3 using Y. lipolytica and industrialized it in 2010. |
