| 학회 |
한국공업화학회 |
| 학술대회 |
2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
22권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Characteristic analysis of natural antioxidant agent-encapsulated Chitosan Microsphere for protection against ROS and enhanced bioavailability |
| 초록 |
The reactive oxygen species (ROS) have been caused to many diseases and aging in human life-span. To solve these issues, natural anti-oxidant used for the removal of ROS has a potential such as immune effect, anti-inflammatory, anti-oxide, anti-cancer effective and low toxic. However, one self of antioxidant has a problem such as low bioavailability in body and high toxicity. To overcome these problems, we prepared to natural antioxidant-encapsulated chitosan microsphere (AECM) by using spray dry method. Its chemical structure was analyzed by 1H-NMR and FT-IR. Also, morphological property and particle size of AECM were observed by SEM, which showed that had a spherical shape and 2 ~ 8 ㎛ size. and, its cytotoxicity was accomplished by MTT assay and it confirmed that had not toxicity. These results suggest that AECM can effectively remove to ROS with low toxicity and enhanced bioavailability. (NRF-2016H1D5A1910499). |
| 저자 |
남충현1, 정경원1, 안준혁1, 박준규2, 정영일3, 나재운1
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| 소속 |
1순천대, 2시지바이오, 3양산부산대 |
| 키워드 |
Chitosan; Bioavailability; Microsphere; Natural antioxidant; Reactive Oxygen Species(ROS)
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| E-Mail |
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