| 초록 |
To date, diverse surface treatment methods have been used to provide titanium (Ti)-mediated medical device with enhanced biocompatibility and bioactivity. However, most approaches are based on the solvent coating method, which has several drawbacks including irregular thickness and low interfacial adhesion between the coating and the medical device surface. Herein, we develop a dopamine-mediated nanoparticle-immobilized Ti surface that can release osteogenic bioactive agents in a controlled manner. The immobilization of the nanoparticles onto the surface of Ti substrates was confirmed by various analytical tools, such as Fe-SEM, UV-Vis spectra, and contact angle. The release of osteogenic bioactive agents lasted for up to 21 days. Surface functionalization of Ti with the nanoparticle releasing system may provide the better performance to various bioactive medical devices. |
