| 학회 |
한국공업화학회 |
| 학술대회 |
2016년 가을 (10/26 ~ 10/28, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 |
20권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Surface Engineering of Titanium with Osteogenic Agent-Releasing Nanoparticles |
| 초록 |
Surface modification of titanium is critical in generating bioactive osteogenic surface of medical devices. The surface-releasing systems that enable to accelerate the osseointegration of dental implants have been widely explored. Especially, the surface immobilization of nanoparticles that can control the release of bioactive molecules has emerged as a promising technique. Herein, we develop a nanoparticle-immobilized titanium surface that can release simvastatin in a controlled manner. The simvastatin-loaded nanoparticles were prepared by self-assembly of 5-cholanic acid-conjugated glycol chitosan in the presence of simvastatin. The successful immobilization of nanoparticles onto titanium surfaces was confirmed by FE-SEM and XPS. The release of simvastatin lasted for up to 20 days. These results suggest that the nanoparticle immobilization technique can be tailored for the sustained release of various bioactive agents from the diverse medical devices. |
| 저자 |
제갈준호, 김다은, 이홍재, 이상천
|
| 소속 |
경희대 |
| 키워드 |
Dopamine; Simvastatin; Surface engineering
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| E-Mail |
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