| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 가을 (10/07 ~ 10/08, 대구 EXCO) |
| 권호 |
35권 2호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Synthesis and characterization of Dual Stimuli Sensitive PEG-g-Poly(NIPAAm) |
| 초록 |
We prepared a double stimuli responsive PEG-g-NIPAAm copolymer that responded to change in temperature and pH. We have designed and synthesized the PEG-g-NIPAAm copolymer that can be generated from the pH-dependent progressive hydrolysis of a benzoic-imine linker in the micelle-forming amphiphilic polymer. NIPAAm was copolymerized with a known quantity of DEA to form a poly(NIPAAmDEA) copolymer and was subsequently grafted with PEG-g- benzoic acid. The LCST of the PEG-g-NIPAAm was depended on the pH and temperature. The LCST of the polymer was decreased by increasing pH. The pH-dependent LCST and particle size was confirmed by cloud-point and DLS method. The resulting series of the PEG-g-NIPAAm were also investigated for their dynamic water contact angles. Responsiveness to combination of stimulus provides the possibility of achieving location specific delivery. |
| 저자 |
김인식, 조선애, 박성영
|
| 소속 |
충주대 |
| 키워드 |
pH sensitive; temperature sensitive; benzoic imine; graft copolymer
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| E-Mail |
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