| 초록 |
Fluorescent probes require high brightness and photostability for cell imaging and treatment. We recently developed a series of lysosome-targeted porphyrin probes consisting of lipophilic alkyl groups for high cell-membrane permeability and azacyclic moiety for targeting lysosomes. To figure out the ability of each group, fluorescent probes which have only lipophilic alkyl group and only azacyclic moiety were introduced. All compounds were newly synthesized with Rothemund-Lindsey condensation and characterized by UV-vis, fluorescence spectroscopy, Mass spectrometry, 1H-NMR and cyclic voltammetry. We report the synthesis and photophysical properties of azacyclic substituted porphyrin fluorescent probes. |
