| 학회 |
한국고분자학회 |
| 학술대회 |
2011년 가을 (10/06 ~ 10/07, 김대중 컨벤션센터) |
| 권호 |
36권 2호 |
| 발표분야 |
Polymer Directed Assembly |
| 제목 |
Novel designed nanostructures ; cyclic amphiphile peptides |
| 초록 |
Self-assembled peptides have been well known as promising biomaterials. Peptides have the advantages such as biocompativity and structures. Peptides have been designed to have linear figure. For the purpose of controlling the self-assembly processes and nanostructures, novel peptide different from traditional figure, are expected to build up novel nanostructure. Cyclic peptides are one of the building blocks that have unique morphological features and more constrained property. Amphiphile molecules possess hydrophilic/phobic parts on two ends. In contrast, the hydrophobic/philic parts are located on two opposite faces in facial amphiphiles. We suggest novel peptides in which these properties are combined. We have investigated the structures and features of the novel self-assembling cyclic amphiphile peptides. This approach shows the characteristic nanostructure formations. These special structures have hollow spaces in the core and should be useful for the intracellular delivery system. |
| 저자 |
최성주, 임용범
|
| 소속 |
연세대 |
| 키워드 |
peptide; self-assembly; amphiphile
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| E-Mail |
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