화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2011년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터)
권호 15권 1호
발표분야 신진과학자포럼
제목 Biological behavior, medicinal application, and environmental toxicity of nanoparticles
초록 Recent attention has been focused on nanomaterials due to their broad potential for biological and medical applications.Nanoparticles fabricated from metals or polymers have been used to enhance the quality of biomedical images by increasing contrast of specific targets.Moreover, nanomaterials have been combined with medicines in an effort to prolong their in vivo half-lives.Most research into medical applications of nanoparticles has involved injecting them into an animal.We have found that polystyrene, metal, and fullerene nanoparticles can undergo in vivo dispersion through oral administration or transdermal delivery.Using nematode C. elegans, it was found that orally administered nano-size clusters pass through the pharynx and are taken up into the intestine.
저자 최신식
소속 명지대
키워드 Nanoparticle; C. elegans; endocytosis; transdermal delivery; toxicity
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