| 학회 |
한국공업화학회 |
| 학술대회 |
2020년 가을 (10/28 ~ 10/30, 광주 김대중컨벤션센터(Kimdaejung Convention Center)) |
| 권호 |
24권 1호 |
| 발표분야 |
포스터-생체재료 |
| 제목 |
Cytocompatible and Photostable Carbon Nanodots for Cell Imaging |
| 초록 |
Recently, zero-dimensional carbon dots (C-dots) with unique fluorescent properties extensively tested for bioimaging applications. However, the typical sizes of C-dots reported in the literature are within 1-6 nm, which makes them difficult to separate, purify and collect. Therefore, the current synthesis methodologies of fluorescent carbon nanomaterials require further improvement. In this study, fluorescent carbon nanoparticles (CNPs) with a quantum yield of 6.08% have been synthesized using a hydrothermal method within a short period of time (t = 30 min). Fluorescence spectroscopy (FS) revealed that CNPs demonstrate excellent photostability that is suitable for prolonged bioimaging applications. Cytotoxicity study with L-929 fibroblastic cells showed that CNPs are nontoxic even at relatively high concentrations up to 250 µg/ml. Strong green fluorescence signal observed from L-929 cells suggested that CNPs can be utilized for in-vitro tissues/cells bioimaging applications. |
| 저자 |
강문성1, 이석현1, 박원정1, 이지은1, 김봉주2, Timur Sh. Atabaev3, 한동욱1
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| 소속 |
1부산대, 2서울대, 3Nazarbayev Univ. |
| 키워드 |
Bioimaging; Carbon nanodot; Cytocompatibility
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| E-Mail |
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