| 학회 |
한국고분자학회 |
| 학술대회 |
2007년 봄 (04/12 ~ 04/13, 제주 ICC) |
| 권호 |
32권 1호 |
| 발표분야 |
나노바이오기술용 고분자(의료용 고분자 부문위원회) |
| 제목 |
Sol-gel Transition and Micellization of Multi-arm Star-shaped Block Copolymers |
| 초록 |
Biodegradable temperature-sensitive copolymers of PEG and polyester such as poly(L-lactide), poly(DL-lactide), poly(ε-caprolactone), and poly (DL-lactide-co-glycolide) were studied as drug delivery systems by many researchers. These polymers have the advantageous properties such as amphiphilicity, self-aggregating properties, temperature-sensitivity, nontoxicity, and biodegradability. Our group developed temperature-sensitive biodegradable multi-arm star-shaped block copolymers having the poly(DL-lactic acid-co-glycolic acid) (PLGA) block and poly(ethylene glycol) (PEG) to investigate the effect of architecture on the micellization and gelation behavior. We expect them to have other specific properties due to their multi-arm star-shaped architecture. |
| 저자 |
이수정1, 김성철1, 박상엽2, 한보령3
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| 소속 |
1한국과학기술원, 2삼양사, 3LG Chem. |
| 키워드 |
sol-gel transition; biodegradable polymer; DDS
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| E-Mail |
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