| 학회 |
한국공업화학회 |
| 학술대회 |
2015년 가을 (11/04 ~ 11/06, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 |
19권 2호 |
| 발표분야 |
유용물질 자원화를 위한 이산화탄소의 생물학적 이용 (KCRC 특별세션) |
| 제목 |
C1 Biorefinery by Designer Microbes |
| 초록 |
The designer microbes are a key biological technology that can be used for biorefinery. The use of complexed enzyme systems is one of the strategies for effective bioresources utilization and offers considerably greater potential through a highly ordered structural organization that enables enzyme proximity synergy. Carbon monoxide (CO) was successfully efficiently converted by functional complexes containing carbon monoxide dehydrogenase and carbon monoxide sensing heme protein with enhanced CO binding affinity. Carbon monoxide sensing heme protein acts as mediator for increasing of carbon monoxide dehydrogenase activity by substrate proximity and assembled complexes caused an efficiently conversion of CO gas with aid of Carbon monoxide sensing heme protein. An enzyme complex for biological conversion of CO to CO2 was anchored on the cell surface of CO2-utilizing Ralstonia eutropha and successfully showed 3.3-fold increased conversion efficiency. These results suggest that the complexed system may be a promising strategy for C1 biorefinery as biological tools. |
| 저자 |
한성옥 |
| 소속 |
고려대 |
| 키워드 |
C1 Biorefinery; Designer Microbes; Enzyme complex; Carbon monoxide
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| E-Mail |
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