| 학회 |
한국공업화학회 |
| 학술대회 |
2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
22권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Study on the Effect of beta-Glucan Loading in Chitosan Scaffold on Osteoblast and Release Kinetics |
| 초록 |
Chitosan is a naturally-derived polysaccharide composed of D-glucosamine and N-acetyl-D-glucosamine and obtained from chitin shells of crustaceans by treating with an alkaline substance. Chitosan has been widely used as a number of biomedical uses. Chitosan can be used as hemostatic bandage, antibacterial agent, and drug carrier. In this study, we investigated we prepared -glucan with CHN scaffold and evaluated the efficacy of drug loading and release pattern. The physical and chemical properties of mineralized chitosan scaffold were examined using various analytical methods. Biocompatibility of the scaffold was evaluated in terms of viability and differentiation using osteosarcoma MG63 cells. Our results demonstrated that the biomimetically mineralized chitosan scaffold can be potentially used for the preparation of artificial bone substitute. |
| 저자 |
xumengcan, 윤다솜, 서종휘, 이재학, 한승우, 이우걸
|
| 소속 |
단국대 |
| 키워드 |
Chitosan; Scaffold; b-glucan; HPLC
|
| E-Mail |
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