| 학회 |
한국공업화학회 |
| 학술대회 |
2019년 봄 (05/01 ~ 05/03, 부산 벡스코(BEXCO)) |
| 권호 |
23권 1호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Polydopamine Coated Multi-Layered PCL Fiber as a Drug Delivery Carrier |
| 초록 |
the spontaneous formation of multi-layers by an electrospinning technique is an unconventional result considering that conventional electrospinning generates a non-discrete, continuous fibrous structure. Dopamine was used as a salt during the fabrication by electrospinning to fabricate multi-layered PCL fiber. The salts are conventionally removed from the fabricated fiber after fabrication. In this study, we have studied the uniform coating of fiber surface by polymerizing dopamine released from the multi-layered PCL fiber. the multi-layered PCL fiber uniformly coated by polydopamine was characterized by SEM, drug release profile in different pH conditions. Also, Adeno-associated virus (AAV) can be attached to the surface of the coating to enable sequential delivery of surface AAV and fiber internal drug. This multi-layered PCL fiber uniformly coated by polydopamine will contribute significant advancements into drug release control and gene therapy. |
| 저자 |
오석민, 김유진, 이희형, 한지나, Lau Zheng Rong, 장재형
|
| 소속 |
연세대 |
| 키워드 |
생체재료 |
| E-Mail |
|
