| 학회 |
한국고분자학회 |
| 학술대회 |
2009년 가을 (10/08 ~ 10/09, 광주과학기술원 오룡관) |
| 권호 |
34권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Preparation of biofunctional electrospun composite nanofibers for bone tissue engineering |
| 초록 |
Electrospinning has recently gained a new motive force due to the introduction of the concept of biofunctional electrospun composite nanofibers that biomimic the extracellular matrix (ECM) of native tissue. In this study, we developed micro-porous and nanofibrous PLA/gelatin composite scaffolds using ultra-sonication and thermally induced phase separation (TIPS). Bone morphogenic protein 2 (BMP-2) was loaded on the surface of heparin immobilized composite scaffold to regenerate bone tissue. The morphological and physical properties were characterized. Mesenchymal stem cells (MSCs) were seeded and cultured on the composite scaffold and fully characterized its osteogenesis potential |
| 저자 |
이정복1, 허동녕2, 윤영필1, 김성은2, 권일근1
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| 소속 |
1경희대, 2치의학전문대 |
| 키워드 |
bone; nanofiber; three dimensional (3D); BMP-2; mesenchymer stem cells (MSCs)
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| E-Mail |
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