화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2010년 봄 (04/08 ~ 04/09, 대전컨벤션센터)
권호 35권 1호
발표분야 세포기능조절 고분자(의료용 고분자 부문위원회)
제목 Preparation and Characterization of Silk Fibroin/Gelatin scaffolds for tissue engineering
초록 Silk Fibroin is non-toxic, non-immunogenic and has been demonstrated to support cell and tissue growth. Gelatin is natural material derived from collagen by hydrolysis and has almost identical composition as that of collagen. Silk Fibroin/Gelatin scaffold can be fabricated by using the freeze-drying method. The Silk Fibroin prepared by crosslinking with or without 2.5% glutaldehyde was applied to 4% gelatin for Establishment of the manufacturing processes of the scaffolds. After Silk Fibroin prepared by 0.1, 0.2, 0.3g was applied to 2, 4, 8% gelatin and crosslinked by 0.25, 1, 2.5 mM of glutaldehyde. The Silk Fibroin scaffold was characterized using SEM, water absorption ability, DSC and WST. In conclusion, Silk Fibroin/Gelatin scaffold may serve as a potential cell delivery vehicle and a structural basis for tissue engineering. This research was supported by WCU(R31-20029).
저자 김혜린, 송재은, 박현진, 정선영, 고마음, 홍민성, 홍동현, 조한수, 이동원, 강길선
소속 전북대
키워드 Silk Fibroin; Gelatin; Scaffold; Tissue Engineering
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