| 학회 |
한국고분자학회 |
| 학술대회 |
2020년 가을 (10/05 ~ 10/08, 부산컨벤션센터(BEXCO)) |
| 권호 |
45권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
In Situ Crosslinked Chitosan/Poly (ethylene Glycol) Hybrid Hydrogel with Controllable Physicochemical Properties |
| 초록 |
Chitosan has been widely used as biomaterials due to versatile properties. However, the inherent brittle properties are still hard to control. To overcome these, PEG has been used for flexible mechanical properties. Although the incorporation of PEG into chitosan has been developed, studies on various parameters of PEG have not been conducted. In this study, we prepared injectable chitosan/PEG hybrid hydrogels using enzyme mediated cross-linking. Physicochemical properties of hydrogel were investigated by varying the parameters of PEG (e.g. content, M.W., geometry). The hydrogels were fully characterized and cyto-compatible. It was found that the various parameters of PEG in hybrid hydrogels could control their physicochemical characteristics. In conclusion, chitosan/PEG hybrid hydrogels with tunable physicochemical properties are expected to be a promising biomaterial for various applications. Acknowledgement: [MOTIE/KEIT] 10062079, 2019R1A6A1A11051471 |
| 저자 |
황진영1, 정하영1, 박기동1, Le Thi Phuong1, 황보경희2, 배진우2
|
| 소속 |
1아주대, 2(주)제노스 |
| 키워드 |
in situ; chitosan; PEG; hybrid; hydrogel; Physicochemical
|
| E-Mail |
|
